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Medical Letter (Medletter)
2023, Volume 1, Issue 3 : 1-6
Research Article
Predictors of Acute Coronary Syndrome Outcomes: A Multicenter Analysis of Clinical, Biochemical, and Treatment-Related Factors
 ,
 ,
1
Department of Cardiology, Northbridge University Hospital, Boston, USA
2
Department of Internal Medicine, Global Health Research Institute, London, UK
3
Department of Cardiovascular Sciences, Western Medical University, Sydney, Australia
Abstract

Background

Acute Coronary Syndrome (ACS) remains one of the leading causes of morbidity and mortality worldwide. Early identification of factors predicting clinical outcomes is essential for improving treatment strategies and patient survival.

Objective

To identify clinical, laboratory, and treatment-related predictors associated with outcomes among patients presenting with Acute Coronary Syndrome.

Methods

A multicenter observational study was conducted involving 650 patients admitted with ACS. Demographic characteristics, cardiovascular risk factors, laboratory parameters, electrocardiographic findings, treatment modalities, and clinical outcomes were evaluated. Multivariate logistic regression was used to identify independent predictors of adverse outcomes.

Results

The mean age of participants was 61.8 ± 11.4 years. Adverse outcomes occurred in 22.6% of patients. Independent predictors included advanced age (OR=2.14), diabetes mellitus (OR=1.87), elevated cardiac troponin levels (OR=2.56), reduced left ventricular ejection fraction (OR=3.11), delayed reperfusion therapy (OR=2.72), and chronic kidney disease (OR=1.94). Early percutaneous coronary intervention significantly improved survival (p<0.001).

Conclusion

Clinical outcomes following ACS are influenced by multiple patient-related and treatment-related factors. Early risk stratification and prompt intervention remain critical for reducing mortality and improving long-term cardiovascular outcomes.

 

Keywords
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